Position
Salary

How much does a Principal Scientist make?

The average salary for a Principal Scientist is $170,890 per year in the US.

The role of a Principal Scientist is both challenging and rewarding. Job seekers who pursue this path often find it well worth the effort. Principal Scientists lead research and development in their fields. They earn a strong salary that reflects their expertise and the impact they have on their companies.

Principal Scientists have many years of experience and advanced degrees. Their work often involves complex problem-solving and innovation. According to recent data, the average yearly salary for a Principal Scientist is about $170,890. This figure represents the midpoint of what many professionals in this role earn. However, salaries can vary based on many factors. These include location, industry, and specific skills. For example, those in high-demand industries or major cities may earn more. Also, those with specialized skills often command higher salaries.

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What are the highest paying cities for a Principal Scientist?

Job seekers aiming for Principal Scientist roles should know that top-paying cities offer excellent opportunities. San Jose, CA, leads with an average salary of $220,723. Cities like San Francisco, CA, and Seattle, WA, also provide high salaries, with averages above $180,000. Other notable cities include Boston, MA, and San Diego, CA, with average salaries above $164,000.
Graph displaying highest paying cities salaries for Principal Scientist jobs, highlighting San Jose, CA with the highest at $220,723 and San Diego, CA with the lowest at $164,669.
  1. San Jose, CA
    Average Salary: $220,723
    San Jose offers a dynamic environment for professionals with roles focusing on tech innovation. Companies like Google and Intel seek experts to drive research and development. The competitive salary reflects the city's demand for skilled talent.
    Find Principal Scientist jobs in San Jose, CA


  2. San Francisco, CA
    Average Salary: $188,413
    In San Francisco, career opportunities abound in the tech sector. Giants such as Salesforce and Dropbox value innovative minds to lead scientific projects. The city's vibrant atmosphere supports career growth and discovery.
    Find Principal Scientist jobs in San Francisco, CA


  3. Seattle, WA
    Average Salary: $184,076
    Seattle presents a unique blend of tech and nature. With companies like Amazon and Microsoft, roles focus on cutting-edge research. The city's welcoming environment supports professional and personal growth.
    Find Principal Scientist jobs in Seattle, WA


  4. Boston, MA
    Average Salary: $178,855
    Boston is a hub for innovation, with biotech firms like Biogen and Genzyme looking for leading experts. The city offers a rich blend of academic collaboration and industry application, making it an exciting place to work.
    Find Principal Scientist jobs in Boston, MA


  5. San Diego, CA
    Average Salary: $164,669
    San Diego's mild climate makes it a pleasant place to work in science. Companies like Illumina and Gilead Sciences value research that pushes boundaries. The city combines a strong economy with a high quality of life.
    Find Principal Scientist jobs in San Diego, CA

What are the best companies a Principal Scientist can work for?

Gilead Sciences, Merck, and Genentech offer top salaries for Principal Scientist roles. Their average pay exceeds $200,000 annually. These companies value scientific expertise and innovation, making them attractive for career growth. Walmart, Johnson & Johnson, and Bristol Myers Squibb also provide competitive salaries for Principal Scientists. They average more than $150,000 each year. These firms are known for their commitment to research and development, which is crucial for scientific advancement.
Graph displaying best paying company salaries for Principal Scientist jobs, highlighting Gilead Sciences with the highest at $219,635 and Eli Lilly with the lowest at $112,389.
  1. Gilead Sciences
    Average Salary: $219,635
    Gilead Sciences offers rewarding Principal Scientist roles across its locations. These positions require expertise in drug development and research. Gilead operates globally with key offices in the U.S., Europe, and Asia.


  2. Merck
    Average Salary: $211,407
    Merck is known for its innovation in health. Principal Scientists here lead research in areas like vaccines and pharmaceuticals. Merck’s global presence includes the U.S., Europe, and other key markets.


  3. Genentech
    Average Salary: $202,568
    Genentech, a Roche company, offers Principal Scientist roles focused on biotechnology and pharmaceuticals. Genentech operates internationally with major offices in the U.S. and other countries.


  4. Walmart
    Average Salary: $197,175
    Walmart provides opportunities for Principal Scientists in supply chain innovation. With locations in the U.S. and globally, Walmart offers dynamic environments for scientific research.


  5. Johnson & Johnson
    Average Salary: $163,209
    Johnson & Johnson offers diverse Principal Scientist positions in medical devices and pharmaceuticals. Operating in North America, Europe, and Asia, J&J focuses on health innovation.


  6. Bristol Myers Squibb
    Average Salary: $160,885
    Bristol Myers Squibb provides roles for Principal Scientists in drug discovery and development. The company is active in the U.S., Europe, and other markets with a focus on therapeutics.


  7. Regeneron
    Average Salary: $158,933
    Regeneron offers Principal Scientist jobs in gene therapy and biotechnology. They have major operations in the U.S. and other regions, focusing on scientific advancement.


  8. Novartis
    Average Salary: $156,656
    Novartis provides opportunities for Principal Scientists in pharmaceuticals and biotechnology. Operating in North America, Europe, and Asia, Novartis is dedicated to improving health outcomes.


  9. Eli Lilly
    Average Salary: $112,389
    Eli Lilly offers Principal Scientist roles in research and drug development. The company is present in North America, Europe, and other regions, focusing on innovative therapies.

How to earn more as a Principal Scientist?

Increasing your earnings as a Principal Scientist requires a mix of skill, experience, and strategy. A well-rounded approach can help professionals at this level maximize their potential income. Focus on these key areas to see results.

First, invest in ongoing education and certifications. The field of science is always evolving. Staying updated with the latest trends and technologies can make you more valuable. Relevant certifications can also open doors to higher-paying positions. Second, build a strong professional network. Connections in your industry can lead to better job opportunities and salary negotiations. Attend conferences, join professional groups, and engage with peers online. Third, take on leadership roles. Experience in managing projects and leading teams can make you eligible for higher positions. Seek out roles that offer opportunities for advancement and increased responsibility.

Apart from these, consider these factors to boost your salary. Seek roles in high-demand fields. Areas like biotech, pharmaceuticals, and artificial intelligence often offer higher pay. Finally, negotiate your salary confidently. Research market rates and be prepared to discuss your worth during interviews.

Look at these factors for earning more as a Principal Scientist:

  1. Invest in education and certifications.
  2. Build a strong professional network.
  3. Take on leadership roles.
  4. Choose high-demand fields.
  5. Negotiate salary confidently.

Currently 52 Principal Scientist job openings, nationwide.

How's the job market for a Principal Scientist in the US?

Learn what a Principal Scientist does, how to become one, and understand the job outlook. Get simple steps to start your career as a Principal Scientist today.
Position
Overview
Principal Scientist
52 Job Openings