Boston, MA, offers the highest average salary for Safety Director jobs, reaching up to $201,114 per year. This city's robust economy and diverse industries drive higher compensation packages. Columbus, OH, follows closely with an average salary of $142,821, providing strong opportunities for safety professionals. Denver, CO, Chicago, IL, and Atlanta, GA, also offer competitive salaries for Safety Director positions. Denver provides a high average salary of $131,382, while Chicago and Atlanta follow with salaries of $130,879 and $127,015, respectively. These cities combine growing industries and safety needs, attracting skilled safety directors.