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What is the average salary in South San Francisco, CA?

The average salary in South San Francisco, CA is $85,235 per year.

Job seekers looking at South San Francisco, CA, will find the average yearly salary to be $85,235. This salary figure reflects a strong job market with various industries contributing to the overall economic health. Notable industries include technology and healthcare, which often offer competitive wages.


The distribution of salaries in South San Francisco is quite diverse, with many job opportunities clustered around the middle to upper salary brackets. The top earners in the region can make up to $255,000 per year. The breakdown shows that a significant portion of jobs falls within the higher salary ranges, offering attractive options for professionals seeking growth and stability.

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What are the best paying jobs in South San Francisco, CA?

South San Francisco offers several high-paying job opportunities for skilled professionals. Software Engineers top the list with an average salary of $175,983 annually. Registered Nurses and Technical Project Leads also enjoy competitive salaries, with averages of $136,972 and $133,127, respectively. Other well-paying jobs in the area include Scientists, General Managers, and Research Associates. These roles provide a chance to earn $114,402, $94,220, and $84,584 per year, respectively. A career in these fields can offer both financial stability and professional growth in a vibrant tech and healthcare hub.
Graph displaying best paying job salaries in South San Francisco, CA, highlighting Software Engineer with the highest at $175,983 and Preschool Teacher with the lowest at $56,026.
  1. Software Engineer
    Average Salary: $175,983
    This role involves designing, coding, and testing software applications. Many tech firms, including biotech and healthcare companies, seek skilled engineers to develop innovative solutions. Opportunities often include collaboration with cross-functional teams to enhance product offerings.
    Find Software Engineer jobs in South San Francisco, CA


  2. Registered Nurse
    Average Salary: $136,972
    Caring for patients and providing medical care, nurses work in hospitals, clinics, and research facilities. They often work closely with doctors and other healthcare professionals. Many local facilities offer specialized care and cutting-edge medical treatments.
    Find Registered Nurse jobs in South San Francisco, CA


  3. Technical Project Lead
    Average Salary: $133,127
    This role requires managing technical projects from start to finish. It involves coordinating with teams, setting timelines, and ensuring project goals are met. Companies in biotech and tech sectors look for leaders who can drive projects with efficiency and precision.
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  4. Scientist
    Average Salary: $114,402
    Scientists conduct research to advance knowledge and develop new technologies. They often work in laboratories, focusing on areas like biotechnology, pharmaceuticals, and environmental science. Their work can lead to breakthroughs that benefit society as a whole.
    Find Scientist jobs in South San Francisco, CA


  5. General Manager
    Average Salary: $94,220
    This role oversees daily operations and manages staff to ensure a business runs smoothly. Managers work in various industries, including retail, hospitality, and tech. They focus on achieving business goals and improving team performance.
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  6. Research Associate
    Average Salary: $84,584
    Research Associates support scientists and engineers by conducting experiments and analyzing data. They work in labs and research facilities, often contributing to significant scientific discoveries. This role requires strong analytical skills and attention to detail.
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  7. Sales Manager
    Average Salary: $82,920
    Sales Managers lead a team to achieve sales targets. They develop strategies, train staff, and analyze market trends. Companies in tech and healthcare need effective sales managers to drive growth and customer engagement.
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  8. Behavior Analyst
    Average Salary: $82,110
    Behavior Analysts assess and improve behaviors through applied techniques. They work in schools, clinics, and private practices. Their goal is to help individuals develop skills and lead more fulfilling lives.
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  9. Maintenance Technician
    Average Salary: $63,507
    Maintenance Technicians ensure buildings and equipment are running smoothly. They handle repairs and preventive maintenance. This role is vital in various settings, from offices to manufacturing plants.
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  10. Preschool Teacher
    Average Salary: $56,026
    Preschool Teachers create a nurturing environment for young children. They plan activities to help children develop social and cognitive skills. Many local schools focus on early childhood education to prepare students for future success.
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What are the best paying jobs in South San Francisco, CA without a degree?

South San Francisco offers several high-paying positions that do not require a college degree. Line cooks make around $44,404 per year, while servers earn about $43,218 annually. Housekeeping staff can expect to bring in approximately $42,019, followed by baristas at around $41,283. Both dishwashers and service team members also see competitive salaries, earning roughly $39,749 and $39,412, respectively. These roles provide good earning potential and are accessible without a degree. This makes them great options for job seekers looking to start or advance their careers without additional educational requirements. Each of these jobs offers a stable income and the chance to gain valuable experience in a bustling city.
Graph displaying best paying job salaries in South San Francisco, CA without a degree, highlighting Line Cook with the highest at $44,404 and Service Team Member with the lowest at $39,412.
  1. Line Cook
    Average Salary: $44,404
    This role involves preparing meals quickly in a fast-paced kitchen. They often work in restaurants, hotels, or catering companies. They need to follow recipes and maintain kitchen cleanliness.
    Find Line Cook jobs in South San Francisco, CA


  2. Server
    Average Salary: $43,218
    Servers welcome guests, take orders, and serve food and drinks. They work in restaurants and cafes. This job requires good communication and teamwork skills.
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  3. Housekeeping
    Average Salary: $42,019
    This role includes cleaning rooms and common areas in hotels, motels, and other lodging facilities. They need to be detail-oriented and efficient. Housekeeping staff ensure guests have a clean environment.
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  4. Barista
    Average Salary: $41,283
    Baristas prepare and serve coffee and other beverages in coffee shops. They create drinks based on customer preferences. This role involves customer service and attention to detail.
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  5. Dishwasher
    Average Salary: $39,749
    Dishwasher cleans dishes, utensils, and kitchen equipment. They work in restaurants and food service. They need to work well under pressure and follow safety guidelines.
    Find Dishwasher jobs in South San Francisco, CA


  6. Service Team Member
    Average Salary: $39,412
    Service team members help customers at various retail stores. They stock shelves, assist with sales, and ensure a pleasant shopping experience. This role is found in grocery stores, electronics shops, and more.
    Find Service Team Member jobs in South San Francisco, CA

Which companies offer the top salaries in South San Francisco, CA?

Companies in South San Francisco offer competitive salaries for their employees. Top earners work for Calico Life Sciences, Denali Therapeutics, and AbbVie, with average salaries of $199,453, $198,122, and $178,006, respectively. Other companies such as ZipLine, Merck, and Cytokinetics also provide attractive compensation packages. These companies provide an excellent opportunity for professionals looking for rewarding careers. JLL, Twist Bioscience, and Thermo Fisher Scientific offer solid salaries as well, with averages around $110,000 to $134,000. South San Francisco Unified School District is also a notable employer in the region.
Graph displaying company salaries in South San Francisco, CA, highlighting Calico Life Sciences with the highest at $199,453 and South San Francisco Unified School District with the lowest at $98,262.
  1. Calico Life Sciences
    Average Salary: $199,453
    Calico Life Sciences is a research and development company that focuses on aging and longevity. It offers a unique environment and innovative projects for its employees.


  2. Denali Therapeutics
    Average Salary: $198,122
    Denali Therapeutics is a biotechnology company that develops treatments for neurodegenerative diseases. It values creativity and teamwork among its staff.


  3. AbbVie
    Average Salary: $178,006
    AbbVie is a pharmaceutical company that focuses on research and development in therapeutic areas. It provides a supportive and collaborative workplace.


  4. ZipLine
    Average Salary: $177,856
    ZipLine is an autonomous aircraft company that uses drones for delivery services. It offers cutting-edge technology and a forward-thinking culture.


  5. Merck
    Average Salary: $167,742
    Merck is a global pharmaceutical company that develops medicines and vaccines. It offers a dynamic and innovative work environment.


  6. CYTOKINETICS
    Average Salary: $162,349
    CYTOKINETICS is a biopharmaceutical company that focuses on muscle activation and contractility. It provides a collaborative and research-driven atmosphere.


  7. TWIST BIOSCIENCE
    Average Salary: $134,549
    TWIST BIOSCIENCE is a biotechnology company that specializes in synthetic DNA manufacturing. It offers a fast-paced and cutting-edge work environment.


  8. Thermo Fisher Scientific
    Average Salary: $113,513
    Thermo Fisher Scientific is a life sciences company that provides scientific instruments and services. It offers a stable and diverse work environment.


  9. JLL
    Average Salary: $111,285
    JLL is a global real estate services company that offers property management and investment services. It provides a dynamic and collaborative workplace.


  10. South San Francisco Unified School District
    Average Salary: $98,262
    South San Francisco Unified School District is an educational institution that offers a variety of job opportunities for teachers and support staff. It provides a nurturing and collaborative work environment.

How does the cost of living in South San Francisco, CA compare to the national average?

South San Francisco, CA, exhibits a higher cost of living compared to the nationwide average, which is set at 100. Housing costs in South San Francisco stand at 240, indicating that these expenses are 140% higher than the national average. Other categories, including groceries, utilities, transportation, healthcare, and miscellaneous items, also surpass the average but to a lesser extent, ranging from 110% to 130% above the national benchmark.
Cost of living comparison graph for South San Francisco, CA vs. Nationwide: housing 140% higher, groceries 20% higher, utilities 10% higher, transportation 30% higher, healthcare 15% higher, miscellaneous 25% higher.

South San Francisco, CA, has a notably higher cost of living compared to the nationwide average. Housing costs, for instance, are significantly elevated, with an index of 240. This means housing expenses are 140% higher than the national average, where the cost of living index stands at 100. Professionals looking to relocate should be prepared for this substantial increase in their housing budget.


Other expenses in South San Francisco also surpass the national average. Groceries cost 20% more, with an index of 120. Utilities are 10% higher, while transportation costs stand at 30% above the average. Healthcare and miscellaneous expenses are also elevated, with indices of 115 and 125, respectively. This equates to healthcare costs being 15% higher and miscellaneous expenses 25% higher than the average. For job seekers, understanding these percentages can help in budgeting and financial planning.

There are 425 job openings in South San Francisco, CA, today!

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South San Francisco, CA
425 Job Openings