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What is the average salary in South San Francisco, CA?

The average salary in South San Francisco, CA is $84,276 per year.

South San Francisco, CA, offers a variety of job opportunities with competitive salaries. On average, professionals can expect to earn $84,276 per year. Many positions offer above-average wages, particularly in sectors like technology and biotech.


Here are some common industries with their average salaries:

  • Information Technology: $133,765
  • Healthcare: $94,779
  • Manufacturing: $75,286
  • Education: $55,793
  • Retail: $36,300
The data shows that tech and healthcare jobs pay the highest, making these fields very attractive to job seekers.

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What are the best paying jobs in South San Francisco, CA?

South San Francisco, CA, offers some of the highest paying jobs in the region. A software engineer earns an average of about $168,000 per year. Other top paying jobs include registered nurses, technical project leads, and scientists. These roles require specialized skills and often come with excellent benefits. Each of these jobs brings unique challenges and opportunities. Software engineers develop innovative software solutions. Registered nurses provide critical healthcare services. Technical project leads manage projects, ensuring they meet deadlines and stay within budget. Scientists conduct research that can lead to new discoveries. These roles require specific education and experience, but they offer a chance for job satisfaction and financial stability.
Graph displaying best paying job salaries in South San Francisco, CA, highlighting Software Engineer with the highest at $168,129 and Research Associate with the lowest at $84,621.
  1. Software Engineer
    Average Salary: $168,129
    Engineers create and test software. They work for companies like Genentech and Illumina. Their role involves improving software for better performance.
    Find Software Engineer jobs in South San Francisco, CA


  2. Registered Nurse
    Average Salary: $133,696
    Nurses care for patients. They work in hospitals and clinics. Their role includes monitoring patients and administering medications.
    Find Registered Nurse jobs in South San Francisco, CA


  3. Technical Project Lead
    Average Salary: $133,315
    Project leads manage technical projects. They coordinate with teams to meet goals. They work for companies like Gilead Sciences and Regeneron.
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  4. Scientist
    Average Salary: $113,995
    Scientists conduct research and experiments. They work in labs and on projects. They find new ways to improve products and processes.
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  5. General Manager
    Average Salary: $87,894
    Managers oversee daily operations. They ensure the company runs smoothly. They make important decisions and manage staff.
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  6. Sales Manager
    Average Salary: $86,629
    Sales managers lead sales teams. They set sales goals and train staff. They work to increase sales and improve performance.
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  7. Operations Manager
    Average Salary: $85,304
    Operations managers handle business operations. They ensure efficiency and effectiveness. They work closely with staff to improve processes.
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  8. Research Associate
    Average Salary: $84,621
    Associates conduct research. They collect and analyze data. Their work helps companies understand market trends and improve products.
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What are the best paying jobs in South San Francisco, CA without a degree?

Job seekers in South San Francisco, CA, can find several lucrative roles without needing a college degree. Line cooks earn an average of $43,222 annually. Opportunities also exist in housekeeping, where professionals can expect to make around $41,818 per year. Servers and baristas provide excellent earning potential, with average salaries of $41,788 and $40,792, respectively. Service team members and dishwashers can also find stable, well-paying positions, earning around $38,693 and $38,480 each year. These roles offer great financial benefits and various opportunities to gain experience in the workforce.
Graph displaying best paying job salaries in South San Francisco, CA without a degree, highlighting Line Cook with the highest at $43,222 and Dishwasher with the lowest at $38,480.
  1. Line Cook
    Average Salary: $43,222
    In this role, you will prepare meals quickly and safely. You can work at well-known restaurants or food chains in the area. Attention to detail and teamwork are important.
    Find Line Cook jobs in South San Francisco, CA


  2. Housekeeping
    Average Salary: $41,818
    Housekeeping staff keep rooms clean and welcoming for guests. This job requires good organization and a friendly attitude. Many local hotels hire for this position.
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  3. Server
    Average Salary: $41,788
    As a server, you will take orders and serve food to customers. Being friendly and efficient is key. You will work at popular eateries and cafes in the city.
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  4. Barista
    Average Salary: $40,792
    Baristas craft coffee beverages for customers. They work in coffee shops and chains. They need to be quick and know how to use coffee machines well.
    Find Barista jobs in South San Francisco, CA


  5. Service Team Member
    Average Salary: $38,693
    This job includes greeting customers and helping them with their needs. They work at various businesses, including retail and service sectors. Good communication skills are important.
    Find Service Team Member jobs in South San Francisco, CA


  6. Dishwasher
    Average Salary: $38,480
    Dishwashers clean dishes and kitchen tools. They work in busy restaurants and food outlets. Attention to detail and a strong work ethic are needed for this role.
    Find Dishwasher jobs in South San Francisco, CA

Which companies offer the top salaries in South San Francisco, CA?

South San Francisco offers a variety of top-paying companies for job seekers. Among them, Calico Life Sciences stands out with the highest average salary at $196,220. Denali Therapeutics and CYTOKINETICS follow closely, offering average salaries of $192,084 and $170,681 respectively. Other notable companies include Merck, AbbVie, and TWIST BIOSCIENCE, all providing competitive salaries. Merck offers an average of $168,904, AbbVie $154,076, and TWIST BIOSCIENCE $132,915. Thermo Fisher Scientific, South San Francisco Unified School District, See's Candies, and Health Plan of San Mateo also present attractive job opportunities with salaries ranging from $115,772 to $100,611. These figures highlight the many well-paying job options available in South San Francisco.
Graph displaying company salaries in South San Francisco, CA, highlighting Calico Life Sciences with the highest at $196,220 and Health Plan of San Mateo with the lowest at $83,377.
  1. Calico Life Sciences
    Average Salary: $196,220
    Calico focuses on aging and related diseases. It offers competitive salaries and benefits.


  2. Denali Therapeutics
    Average Salary: $192,084
    Denali specializes in neuroscience drug development. It provides a rewarding work environment.


  3. CYTOKINETICS
    Average Salary: $170,681
    This company works on muscle activation and works in muscle-related disease treatment.


  4. Merck
    Average Salary: $168,904
    A global pharmaceutical company, Merck is known for its research and development.


  5. AbbVie
    Average Salary: $154,076
    AbbVie develops innovative treatments for immune and genetic disorders.


  6. TWIST BIOSCIENCE
    Average Salary: $132,915
    This biotech company specializes in DNA synthesis and gene editing.


  7. Thermo Fisher Scientific
    Average Salary: $115,772
    A global leader in scientific instruments and reagents, offering a variety of career opportunities.


  8. South San Francisco Unified School District
    Average Salary: $100,611
    The district provides educational services and employs teachers, administrators, and support staff.


  9. See's Candies
    Average Salary: $95,203
    This family-owned company is known for its delicious candies and sweets.


  10. Health Plan of San Mateo
    Average Salary: $83,377
    This healthcare provider offers various health plans and services to the community.

How does the cost of living in South San Francisco, CA compare to the national average?

South San Francisco, CA, has a higher cost of living compared to the nationwide average, with a cost of living index of 149. The housing index alone stands at 250, significantly impacting the overall index. While groceries, utilities, transportation, healthcare, and miscellaneous expenses are also above the national average, housing is the largest contributor to the elevated cost of living.
Cost of living comparison graph for South San Francisco, CA vs. Nationwide: housing 150% higher, groceries 20% higher, utilities 15% higher, transportation 30% higher, healthcare 10% higher, miscellaneous 5% higher.

The cost of living in South San Francisco, CA, stands significantly higher than the nationwide average. Specifically, the housing index in this area is recorded at 250. This means housing costs in South San Francisco are 150% higher than the national average. For those considering relocating or moving, this can significantly impact their budget.


Other areas of living expenses also show elevated costs. Groceries, for example, have an index of 120, indicating a 20% increase over the national average. Utilities follow closely with an index of 115, which is 15% above the nationwide average. Even transportation costs, indexed at 130, show a 30% rise. Healthcare, however, remains relatively close to the national average with an index of 110, only 10% higher. These statistics highlight the need for careful financial planning when considering a move to South San Francisco.

There are 524 job openings in South San Francisco, CA, today!

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South San Francisco, CA
524 Job Openings