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What is the average salary in South San Francisco, CA?

The average salary in South San Francisco, CA is $85,791 per year.

Job seekers in South San Francisco, CA, can expect a competitive salary landscape. The average yearly salary stands at $85,791. This figure reflects the diverse job opportunities available across various industries. Salaries range widely, offering potential for both entry-level and experienced professionals.


The salary distribution shows a broad spectrum of earnings. The majority of jobs fall between $35,500 and $131,790 annually. This range includes roles in healthcare, technology, and finance. Higher salaries are common in specialized fields such as biotechnology and software development. Job seekers can find rewarding positions that align with their skills and career goals.

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What are the best paying jobs in South San Francisco, CA?

South San Francisco, CA, offers a range of high-paying job opportunities. Software Engineers lead the pack with an average salary of $160,751. This role involves designing and developing software applications. Registered Nurses also earn well, with an average salary of $129,159. They provide critical care and support to patients in various healthcare settings. Other top-paying jobs include Technical Project Leads, Speech Language Pathologists, and Scientists. These roles require specialized skills and education, but they offer competitive salaries. For example, Technical Project Leads earn around $126,527, while Speech Language Pathologists make about $124,880. Scientists, with their research and development work, earn an average of $110,249. These jobs provide stability and good compensation in the South San Francisco job market.
Graph displaying best paying job salaries in South San Francisco, CA, highlighting Software Engineer with the highest at $160,751 and Sales Manager with the lowest at $80,706.
  1. Software Engineer
    Average Salary: $160,751
    This role involves creating software applications. Companies like Genentech and Gilead Sciences offer opportunities. They focus on innovative tech solutions.
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  2. Registered Nurse
    Average Salary: $129,159
    RNs provide patient care and support. They work in hospitals and clinics. South San Francisco has many healthcare facilities.
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  3. Technical Project Lead
    Average Salary: $126,527
    This position involves managing tech projects. Companies like Illumina and Biogen need skilled leads. They ensure projects run smoothly and meet goals.
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  4. Speech Language Pathologist
    Average Salary: $124,880
    SLPs help people with speech and language issues. They work in schools and clinics. South San Francisco has many facilities that need their expertise.
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  5. Scientist
    Average Salary: $110,249
    Scientists conduct research and experiments. They work in labs for companies like Genentech. They focus on developing new medicines and treatments.
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  6. Behavior Analyst
    Average Salary: $88,825
    Behavior analysts study and improve behaviors. They work with schools and clinics. South San Francisco has many places that need their services.
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  7. Research Associate
    Average Salary: $85,143
    Research associates help scientists conduct studies. They work in labs for companies like Illumina. They gather and analyze data.
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  8. General Manager
    Average Salary: $83,944
    General managers oversee business operations. They work in various industries. South San Francisco has many businesses needing their skills.
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  9. Operations Manager
    Average Salary: $82,895
    Operations managers ensure smooth business operations. They work in many sectors. South San Francisco has many companies needing their expertise.
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  10. Sales Manager
    Average Salary: $80,706
    Sales managers lead sales teams. They work in various industries. South San Francisco has many businesses needing their skills.
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What are the best paying jobs in South San Francisco, CA without a degree?

South San Francisco offers several high-paying jobs that do not require a college degree. Line cooks earn the most, with an average salary of $42,909. Other well-paying roles include housekeeping, barista, server, service team member, and dishwasher. These positions provide a good income and can be a great start for those looking to enter the workforce without a degree.
Graph displaying best paying job salaries in South San Francisco, CA without a degree, highlighting Line Cook with the highest at $42,909 and Dishwasher with the lowest at $37,827.
  1. Line Cook
    Average Salary: $42,909
    Line cooks work in a fast-paced kitchen, preparing meals quickly and efficiently. They often work in restaurants and food service companies. This role requires attention to detail and the ability to work well under pressure.
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  2. Housekeeping
    Average Salary: $40,610
    Housekeeping staff ensure cleanliness and order in hotels, motels, and other lodging facilities. They clean rooms, change linens, and maintain a welcoming environment. This job is ideal for those who enjoy a tidy workspace and helping guests feel comfortable.
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  3. Barista
    Average Salary: $40,377
    Baristas prepare coffee and other beverages in cafes and coffee shops. They interact with customers, take orders, and create delicious drinks. This role is perfect for those who love coffee and enjoy serving others.
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  4. Server
    Average Salary: $39,525
    Servers work in restaurants, taking orders and serving food and drinks to customers. They must be friendly and efficient, ensuring a pleasant dining experience. This job is great for those who enjoy social interactions and multitasking.
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  5. Service Team Member
    Average Salary: $38,186
    Service team members assist customers in various settings, such as retail stores or service centers. They provide support, answer questions, and help resolve issues. This role is ideal for those who enjoy helping others and working in a dynamic environment.
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  6. Dishwasher
    Average Salary: $37,827
    Dishwashers clean dishes, utensils, and kitchen equipment in restaurants and food service establishments. They work behind the scenes to keep the kitchen running smoothly. This job is suitable for those who prefer a hands-on role and enjoy a clean workspace.
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Which companies offer the top salaries in South San Francisco, CA?

Job seekers in South San Francisco, CA, can find top-paying opportunities with several companies. Cytokinetics leads the way with an average salary of $170,681. Merck and Cellares also offer competitive salaries, with averages of $155,101 and $151,315, respectively. Other notable employers include AbbVie, Twist Bioscience, and Concentra, which provide average salaries ranging from $145,488 to $128,130. These companies present attractive options for those seeking well-paying jobs in the area.
Graph displaying company salaries in South San Francisco, CA, highlighting CYTOKINETICS with the highest at $170,681 and Health Plan of San Mateo with the lowest at $84,752.
  1. CYTOKINETICS
    Average Salary: $170,681
    Cytokinetics is a biopharmaceutical company focused on muscle health. It offers a competitive salary and benefits.


  2. Merck
    Average Salary: $155,101
    Merck is a global healthcare company. It provides a wide range of benefits and a strong salary package.


  3. Cellares
    Average Salary: $151,315
    Cellares is a biotech company that specializes in cell and gene therapy. It offers a high salary and excellent benefits.


  4. AbbVie
    Average Salary: $145,488
    AbbVie is a research-driven biopharmaceutical company. It provides a competitive salary and a comprehensive benefits package.


  5. TWIST BIOSCIENCE
    Average Salary: $131,376
    Twist Bioscience is a leader in synthetic DNA technology. It offers a good salary and benefits for its employees.


  6. Concentra
    Average Salary: $128,130
    Concentra is a health care company that provides occupational medicine. It offers a solid salary and benefits.


  7. Thermo Fisher Scientific
    Average Salary: $117,421
    Thermo Fisher Scientific is a global leader in serving science. It provides a competitive salary and benefits.


  8. South San Francisco Unified School District
    Average Salary: $100,882
    The South San Francisco Unified School District offers education services. It provides a good salary and benefits for educators.


  9. See's Candies
    Average Salary: $92,579
    See's Candies is a family-owned candy company. It offers a decent salary and benefits for its employees.


  10. Health Plan of San Mateo
    Average Salary: $84,752
    Health Plan of San Mateo provides health insurance services. It offers a fair salary and benefits.

How does the cost of living in South San Francisco, CA compare to the national average?

South San Francisco, CA, has a higher cost of living compared to the nationwide average. The housing index alone is 145% of the national average, while other categories like groceries and utilities are also above the national average. This indicates that living expenses in South San Francisco are significantly higher than the average American city.
Cost of living comparison graph for South San Francisco, CA vs. Nationwide: housing 145% higher, groceries 22% higher, utilities 18% higher, transportation 31% higher, healthcare 10% higher, miscellaneous 30% higher.

South San Francisco, CA, has a higher cost of living compared to the nationwide average. The housing index in South San Francisco is 245, which is 145% of the national average. This means housing costs are nearly 45% higher than the average. Groceries in South San Francisco also cost more, with an index of 122, which is 22% above the national average.


Utilities and transportation in South San Francisco are slightly above the national average. The utility index is 118, which is 18% higher, while the transportation index is 131, 31% higher. Healthcare costs are relatively close to the national average, with an index of 110, which is 10% higher. Miscellaneous expenses also show a modest increase, with an index of 130, which is 30% higher than the national average. These factors combine to make South San Francisco a more expensive place to live compared to the rest of the country.

There are 429 job openings in South San Francisco, CA, today!

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South San Francisco, CA
429 Job Openings