How much does a Registered Nurse make in Cape Girardeau, MO?
In Cape Girardeau, Missouri, Registered Nurses (RNs) earn a solid salary. On average, RNs make about $73,224 per year. This number shows the typical earnings for RNs in the area. Knowing this can help job seekers understand what to expect if they choose this career path.
The salaries for RNs in Cape Girardeau range from $35,530 to $128,000 annually. This wide range means that experienced RNs earn more. Here are the salary figures broken down into percentiles:
- 10% of RNs earn less than $35,530
- 25% of RNs earn less than $43,936
- 50% of RNs earn less than $52,343
- 75% of RNs earn less than $69,155
- 90% of RNs earn less than $111,187
What are the highest paying cities for a Registered Nurse near Cape Girardeau, MO?

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Portageville, MO
Average Salary: $84,070
In Portageville, nurses find a welcoming community where healthcare needs are met with care and compassion. With smaller, close-knit hospitals, nurses build strong relationships with both patients and colleagues. Local employers like Pemiscot Memorial Health Systems offer stable job opportunities.
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Sikeston, MO
Average Salary: $82,019
Sikeston offers a diverse healthcare environment with opportunities to grow professionally. Nurses here enjoy a blend of urban and rural experiences. Sikeston Healthcare and Rehabilitation Center is a prominent employer, providing a supportive work atmosphere.
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Charleston, MO
Average Salary: $81,777
Charleston provides a nurturing environment for nursing careers with a focus on community health. Working here means being part of a tight-knit medical team. St. Francis Medical Center is a key employer, valuing professional development and patient care.
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Caruthersville, MO
Average Salary: $76,724
Caruthersville offers a smaller, more personal healthcare setting where nurses can make a real difference. The community’s healthcare needs are met with dedicated care. Caruthersville Medical Center is a leading employer, emphasizing teamwork and patient well-being.
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Jackson, MO
Average Salary: $76,562
Jackson presents a dynamic healthcare landscape with opportunities to engage in various specialties. Nurses here work in well-equipped facilities. Saint Francis Medical Center is a major employer, offering robust professional growth and patient care.
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Farmington, MO
Average Salary: $75,170
Farmington offers a rural charm with a robust healthcare system. Nurses here enjoy a slower pace with ample opportunities for personal growth. St. Joe’s Health Center is a key employer, fostering a supportive and collaborative work environment.
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Poplar Bluff, MO
Average Salary: $73,612
Poplar Bluff provides a blend of urban and rural healthcare settings. Nurses here work in facilities that emphasize quality care. Poplar Bluff Regional Medical Center is a prominent employer, offering a variety of specialties and strong community ties.
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Marble Hill, MO
Average Salary: $73,400
Marble Hill offers a close-knit healthcare community where nurses are valued for their dedication. Smaller facilities allow for close patient interaction. Marble Hill Medical Center is a leading employer, providing a supportive and family-oriented work environment.
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Advance, MO
Average Salary: $72,662
Advance offers a friendly, community-focused healthcare setting. Nurses here enjoy a slower pace and strong community ties. Advance Medical Center is a key employer, emphasizing teamwork and patient-centered care.
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Hayti, MO
Average Salary: $71,562
Hayti provides a supportive environment for nurses with a focus on community health. Smaller facilities mean close patient interaction and strong teamwork. Pemiscot Memorial Health Systems is a significant employer, valuing professional development and patient care.
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What are the best paying companies for a Registered Nurse in Cape Girardeau, MO?

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Trusted Health
Average Salary: $122,393
Trusted Health offers top pay and benefits for Registered Nurses. They provide jobs across various locations, including Cape Girardeau. They value work-life balance and career growth for their staff.
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Genie Healthcare
Average Salary: $115,107
Genie Healthcare provides competitive salaries for Registered Nurses in Cape Girardeau, MO. They offer flexible shifts and career advancement opportunities. Their focus is on high-quality patient care.
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Favorite Healthcare Staffing
Average Salary: $110,169
Favorite Healthcare Staffing pays well for Registered Nurses in Cape Girardeau. They offer a variety of job settings and focus on professional development. They support their staff with excellent benefits.
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Supplemental Health Care
Average Salary: $99,359
Supplemental Health Care provides attractive salaries for Registered Nurses in Cape Girardeau. They offer diverse job opportunities and focus on patient care. Their benefits package is highly regarded.
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PRN Healthcare
Average Salary: $99,033
PRN Healthcare offers good pay for Registered Nurses in Cape Girardeau. They provide various job opportunities and support career growth. Their team values work-life balance.
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Gifted Healthcare
Average Salary: $97,692
Gifted Healthcare pays well for Registered Nurses in Cape Girardeau, MO. They offer competitive benefits and flexible schedules. Their focus is on providing high-quality patient care.
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Accountable Healthcare Staffing
Average Salary: $96,310
Accountable Healthcare Staffing offers good compensation for Registered Nurses in Cape Girardeau. They provide diverse job opportunities and support professional growth. Their benefits are comprehensive.
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SOUTHEAST BEHAVIORAL HOSPITAL
Average Salary: $93,835
SOUTHEAST BEHAVIORAL HOSPITAL provides a good salary for Registered Nurses in Cape Girardeau. They focus on mental health care and offer supportive work environments. Their benefits are robust.
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OneStaff Medical
Average Salary: $92,364
OneStaff Medical offers competitive pay for Registered Nurses in Cape Girardeau. They provide various job settings and focus on career development. Their staff benefits are attractive.
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Missouri Veterans Home
Average Salary: $87,170
Missouri Veterans Home provides decent pay for Registered Nurses in Cape Girardeau. They focus on care for veterans and offer a supportive work environment. Their benefits include health care and retirement plans.
What are the best paying Registered Nurse related jobs in Cape Girardeau, MO?

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Nurse Practitioner
Average Salary: $155,563
In health clinics and private practices, Nurse Practitioners provide primary and specialty care. Their role involves diagnosing illnesses, prescribing treatments, and coordinating care. They often work closely with doctors and other healthcare professionals.
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Labor and Delivery Registered Nurse
Average Salary: $140,000
These nurses support mothers during childbirth. They monitor the baby’s and mother’s health, provide care before, during, and after delivery. They work in hospitals and birthing centers, ensuring both mother and baby are safe.
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Nurse Supervisor
Average Salary: $139,166
Nurse Supervisors manage nursing teams in various healthcare settings. They ensure patient care meets high standards, handle staff scheduling, and support nurse development. Their role is key in maintaining smooth operations in busy healthcare environments.
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Telemetry Nurse
Average Salary: $114,764
Telemetry Nurses monitor patients’ heart rhythms and other vital signs. They work in specialized units, using advanced technology to ensure patients receive the best care. Their attention to detail helps prevent complications and improve outcomes.
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Advanced Practice Provider
Average Salary: $112,838
Advanced Practice Providers offer a range of medical services. They often work in clinics or hospitals, diagnosing conditions, managing treatments, and providing ongoing care. Their role is crucial in delivering high-quality healthcare services.
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Acute Care Nurse
Average Salary: $106,985
These nurses care for patients with serious or critical conditions. They work in hospitals, providing intensive care and monitoring patients’ progress. Their expertise is vital in managing complex medical situations and improving patient health.
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Intensive Care Unit Registered Nurse
Average Salary: $105,948
ICU RNs provide specialized care to critically ill patients. They monitor vital signs, administer treatments, and support families. Their skills are essential in high-pressure environments, ensuring patients receive the best possible care.
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Traveling Nurse
Average Salary: $104,394
Traveling Nurses work in various locations, providing care where needed most. They often fill short-term positions, gaining diverse experiences. This role allows for flexibility and the chance to explore different healthcare settings.
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Nurse Consultant
Average Salary: $102,500
Nurse Consultants advise healthcare organizations on improving patient care. They analyze data, recommend changes, and support staff training. Their work enhances the quality and efficiency of healthcare services.
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Nurse Case Manager
Average Salary: $70,000
Nurse Case Managers coordinate care for patients with complex needs. They work with doctors, therapists, and families to create care plans. Their goal is to ensure patients receive comprehensive and coordinated care throughout their treatment.
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